LITERATURE ANALYSIS ON THE ROLE OF PHARMACISTS IN DRUG THERAPY MANAGEMENT IN GERIATRIC PATIENTS
Main Article Content
Ita Octafia
Safitri Indah Masithah
This study aims to analyze the role of pharmacists in medication therapy management (MTM) among geriatric patients, focusing on their contributions to optimizing pharmacotherapy, improving patient outcomes, and minimizing drug-related problems (DRPs). Employing a qualitative descriptive design through a literature-based approach, the research systematically reviewed scholarly articles, clinical studies, and official reports published between 2015 and 2025. Data were collected through comprehensive literature tracing and document analysis, then processed using thematic analysis to identify key patterns related to pharmacist interventions in geriatric care. The findings reveal that pharmacist-led activities—including medication reviews, deprescribing, and interprofessional collaboration—substantially reduce DRPs, enhance medication adherence, and improve clinical, functional, and economic outcomes. Moreover, the integration of pharmacists into multidisciplinary teams strengthens therapeutic decision-making and reduces adverse drug events, reinforcing their essential role in patient-centered healthcare systems. The study underscores the theoretical evolution of pharmaceutical care toward an integrated clinical practice model while highlighting economic benefits and enhanced quality of life for elderly patients. It concludes that pharmacists are vital in advancing safe and rational medication use within aging populations. Future research is encouraged to adopt mixed or longitudinal methods to further explore the long-term and cross-cultural impacts of pharmacist-led interventions.
Abraham, D., & P, P. (2024). A Methodological Framework for Descriptive Phenomenological Research. Western Journal of Nursing Research, 47, 125–134. https://doi.org/10.1177/01939459241308071
Baillie, J. (2019). Commentary: An overview of the qualitative descriptive design within nursing research. Journal of Research in Nursing, 25, 458–459. https://doi.org/10.1177/1744987119881056
Bandaranayake, P. (2024). Application of grounded theory methodology in library and information science research: An overview. Sri Lanka Library Review. https://doi.org/10.4038/sllr.v38i2.70
Belotto, M. (2018). Data Analysis Methods for Qualitative Research: Managing the Challenges of Coding, Interrater Reliability, and Thematic Analysis. The Qualitative Report. https://doi.org/10.46743/2160-3715/2018.3492
Bingham, A. (2023). From Data Management to Actionable Findings: A Five-Phase Process of Qualitative Data Analysis. International Journal of Qualitative Methods, 22. https://doi.org/10.1177/16094069231183620
Campbell, A., Coley, K., Corbo, J., Delellis, T., Joseph, M., Thorpe, C., Mcgivney, M., Klatt, P., Cox-Vance, L., Balestrino, V., & Sakely, H. (2018). Pharmacist-Led Drug Therapy Problem Management in an Interprofessional Geriatric Care Continuum: A Subset of the PIVOTS Group. American Health & Drug Benefits, 11(9), 469–478.
Cortejoso, L., Dietz, R., Hofmann, G., Gosch, M., & Sattler, A. (2016). Impact of pharmacist interventions in older patients: A prospective study in a tertiary hospital in Germany. Clinical Interventions in Aging, 11, 1343–1350. https://doi.org/10.2147/cia.s109048
Doyle, L., McCabe, C., Keogh, B., Brady, A., & McCann, M. (2019). An overview of the qualitative descriptive design within nursing research. Journal of Research in Nursing, 25, 443–455. https://doi.org/10.1177/1744987119880234
Fife, S., & Gossner, J. (2024). Deductive Qualitative Analysis: Evaluating, Expanding, and Refining Theory. International Journal of Qualitative Methods, 23. https://doi.org/10.1177/16094069241244856
Freitag, M., Franzen, J., Just, K., Eisert, A., Bollheimer, L., & Laurentius, T. (2024). Pharmacist-Led Medication Management in Acute Geriatric Medicine and Its Associations with Rehospitalizations: A Cohort Study. Gerontology, 70, 914–929. https://doi.org/10.1159/000539710
Gonçalves, J., Ramalhinho, I., Sleath, B., Lopes, M., & Cavaco, A. (2021). Probing pharmacists’ interventions in Long-Term Care: A systematic review. European Geriatric Medicine, 12, 673–693. https://doi.org/10.1007/s41999-021-00469-5
Granikov, V., Hong, Q., Crist, E., & Pluye, P. (2020). Mixed methods research in library and information science: A methodological review. Library & Information Science Research. https://doi.org/10.1016/j.lisr.2020.101003
Hailu, B., Berhe, D., Gudina, E., Gidey, K., & Getachew, M. (2019). Drug related problems in admitted geriatric patients: The impact of clinical pharmacist interventions. BMC Geriatrics, 20. https://doi.org/10.1186/s12877-020-1413-7
Hazen, A., Zwart, D., Poldervaart, J., De Gier, J., De Wit, N., De Bont, A., & Bouvy, M. (2019). Non-dispensing pharmacists’ actions and solutions of drug therapy problems among elderly polypharmacy patients in primary care. Family Practice. https://doi.org/10.1093/fampra/cmy114
Herledan, C., Cerfon, M., Baudouin, A., Larbre, V., Lattard, C., Poletto, N., Ranchon, F., & Rioufol, C. (2023). Impact of pharmaceutical care interventions on multidisciplinary care of older patients with cancer: A systematic review. Journal of Geriatric Oncology. https://doi.org/10.1016/j.jgo.2023.101450
Jimenez, S., Berbegal-Mirabent, J., & De La Torre, R. (2024). How do university libraries contribute to the research process? The Journal of Academic Librarianship. https://doi.org/10.1016/j.acalib.2024.102930
Kalpokaite, N., & Radivojevic, I. (2018). Demystifying Qualitative Data Analysis for Novice Qualitative Researchers. The Qualitative Report. https://doi.org/10.46743/2160-3715/2019.4120
Kim, A., Lee, H., Shin, E., Cho, E., Cho, Y., Lee, H., & Lee, J. (2021). Pharmacist-Led Collaborative Medication Management for the Elderly with Chronic Kidney Disease and Polypharmacy. International Journal of Environmental Research and Public Health, 18. https://doi.org/10.3390/ijerph18084370
Lee, G. H. P., Caton, E., & Ding, A. (2023). Mengevaluasi kompetensi digital untuk apoteker. Penelitian Farmasi Sosial & Administrasi. https://doi.org/10.1016/j.sapharm.2023.01.012
Lin, H., Lin, C., Chang, C., Chou, C., Yu, I., Lin, C., Li, T., Li, C., & Hsieh, Y. (2017). Economic outcomes of pharmacist-physician medication therapy management for polypharmacy elderly: A prospective, randomized, controlled trial. Journal of the Formosan Medical Association, 117(3), 235–243. https://doi.org/10.1016/j.jfma.2017.04.017
Niznik, J., Collins, B., Armistead, L., Larson, C., Kelley, C., Hughes, T., Sanders, K., Carlson, R., & Ferreri, S. (2021). Pharmacist interventions to deprescribe opioids and benzodiazepines in older adults: A rapid review. Research in Social & Administrative Pharmacy. https://doi.org/10.1016/j.sapharm.2021.07.012
Patel, N. (2023). Medication Therapy Management and Medication Adherence For Geriatric Patients. Progress in Medical Sciences. https://doi.org/10.47363/pms/2023(7)e163
Pratt, M. (2025). On the Evolution of Qualitative Methods in Organizational Research. Annual Review of Organizational Psychology and Organizational Behavior. https://doi.org/10.1146/annurev-orgpsych-111722-032953
Silveira, D., & Vicedo, B. (2021). The role of pharmacists in geriatric teams: The time is now. European Geriatric Medicine, 12, 1119–1121. https://doi.org/10.1007/s41999-021-00501-8
Stuhec, M., Bratović, N., & Mrhar, A. (2019). Impact of clinical pharmacist’s interventions on pharmacotherapy management in elderly patients on polypharmacy with mental health problems including quality of life: A prospective non-randomized study. Scientific Reports, 9. https://doi.org/10.1038/s41598-019-53057-w
Stuhec, M., & Lah, L. (2021). Clinical pharmacist interventions in elderly patients with mental disorders in primary care focused on psychotropics: A retrospective pre–post observational study. Therapeutic Advances in Psychopharmacology, 11. https://doi.org/10.1177/20451253211011007
Stuhec, M., & Zorjan, K. (2022). Clinical pharmacist interventions in ambulatory psychogeriatric patients with excessive polypharmacy. Scientific Reports, 12. https://doi.org/10.1038/s41598-022-15657-x
Svahn, S., Gallego, G., Gustafsson, M., & Lindqvist, M. (2025). Geriatric patients’ views on a pharmacist-led follow-up programme after discharge from hospital. Exploratory Research in Clinical and Social Pharmacy, 18. https://doi.org/10.1016/j.rcsop.2025.100597
Togia, A., & Malliari, A. (2017). Research Methods in Library and Information Science. https://doi.org/10.5772/intechopen.68749
Tran-Nguyen, S., & Asha, S. (2024). A collaborative pharmacist-led intervention to prevent hospital readmissions among elderly patients discharged from the emergency department: A retrospective cohort study. Scientific Reports, 14. https://doi.org/10.1038/s41598-024-64968-8
Vila-Henninger, L., Dupuy, C., Van Ingelgom, V., Caprioli, M., Teuber, F., Pennetreau, D., Bussi, M., & Gall, C. (2022). Abductive coding: Theory building and qualitative (re)analysis. Sociological Methods & Research, 53, 968–1001. https://doi.org/10.1177/00491241211067508
Walsh, D., Horgan, A., O’Driscoll, M., Hannan, M., Goggin, C., & Sahm, L. (2024). Reducing potentially inappropriate medication use and patient harm in a dedicated geriatric oncology clinic: A cross-sectional study. International Journal of Pharmacy Practice. https://doi.org/10.1093/ijpp/riae013.024
Whitman, A., Degregory, K., Morris, A., Mohile, S., & Ramsdale, E. (2018). Pharmacist-led medication assessment and deprescribing intervention for older adults with cancer and polypharmacy: A pilot study. Supportive Care in Cancer, 26, 4105–4113. https://doi.org/10.1007/s00520-018-4281-3
Yaacob, N., Loganathan, M., Hisham, N., Kamaruzzaman, H., Isa, K., Ibrahim, M., & Ng, K. (2024). The Impact of Pharmacist Medication Reviews on Geriatric Patients: A Scoping Review. Korean Journal of Family Medicine, 45, 125–133. https://doi.org/10.4082/kjfm.23.0220
Zaij, S., Maia, K., Leguelinel-Blache, G., Roux-Marson, C., Kinowski, J., & Richard, H. (2023). Intervention of pharmacist included in multidisciplinary team to reduce adverse drug event: A qualitative systematic review. BMC Health Services Research, 23. https://doi.org/10.1186/s12913-023-09512-6








